5-Amino-1MQ (50mg Vial)

5-Amino-1MQ is a selective, cell-permeable NNMT (Nicotinamide N-methyltransferase) inhibitor studied primarily in animal and laboratory models.

Preclinical research suggests NNMT inhibition may:

  • Support fat metabolism
  • Help preserve lean muscle mass
  • Increase intracellular NAD⁺ levels
  • Influence SIRT1-related metabolic pathways

Most available data is non-human. Human research is currently very limited. Information is provided for educational and scientific reference only.

Reconstitution Summary (Educational Reference)

  • Vial strength: 50 mg
  • Diluent: 2.0 mL bacteriostatic water
  • Final concentration after reconstitution:
  • “Reconstitution” is a fancy word that just means:

    Mixing powder with water so it becomes liquid

    In research settings:

    • Scientists add special clean water (BACwater) to the vial
    • The powder slowly melts into the water
    • They wait a bit so it mixes evenly

Concentration

  • 50 mg ÷ 2.0 mL = 25 mg/mL

Commonly Referenced Preclinical Dose Range

  • 2.5–5 mg
  • Administered once or twice daily
  • Subcutaneous route is commonly referenced in research discussions
  • Lower doses are typically referenced first, with gradual increases over time

U-100 Syringe Dose Math (Key Answer)

A U-100 insulin syringe = 100 units per 1.0 mL

With a 25 mg/mL concentration:

2 mg dose calculation

  • Volume needed:
    2 mg ÷ 25 mg/mL = 0.08 mL
  • U-100 syringe units:
    0.08 mL × 100 = 8 units

2 mg = 8 units on a U-100 syringe

Quick Recap