MOTS-C (10mg Vial)

MOTS-c is a 16–amino-acid mitochondrial-derived peptide (MDP) involved in metabolic regulation, primarily via AMPK activation.

Preclinical (non-human) research suggests MOTS-c may:

  • Improve insulin sensitivity
  • Increase fat oxidation
  • Enhance exercise capacity
  • Counter age-related metabolic decline

⚠️ No completed human clinical trials exist to date. All dose discussions are extrapolated from non-human preclinical data and presented strictly for educational and scientific reference.

Educational Reconstitution Reference

  • Vial content: 10 mg MOTS-c
  • Diluent: 2.0 mL bacteriostatic water (BAC water)
  • Add BAC water slowly to the vial using sterile technique
  • Allow vial to rest ~20 minutes until fully dissolved
  • Do not shake aggressively
  • “Reconstitution” is a fancy word that just means:

    Mixing powder with water so it becomes liquid

    In research settings:

    • Scientists add special clean water (BACwater) to the vial
    • The powder slowly melts into the water
    • They wait a bit so it mixes evenly

After reconstitution:

  • Total concentration:
    10 mg / 2.0 mL = 5 mg/mL
    (or 5,000 mcg per mL)

U-100 Syringe Concentration Math (Educational)

A U-100 insulin syringe measures 100 units = 1.0 mL

With this dilution:

  • 1 unit = 0.01 mL
  • Each unit = 50 mcg MOTS-c

Typical Preclinical Research Range (Contextual)

  • 200–1,000 mcg once daily
  • Often referenced with gradual titration over several weeks
  • Derived solely from non-human models

Quick Recap