Compound: TB-500 fragment (17-23) (Ac-LKKTETQ)
•Synthetic heptapeptide derived from the actin-binding region of thymosin β4.
•Investigated in laboratory settings related to tissue repair/regeneration.
•Not FDA-approved for human use and commonly labeled for research purposes only.
Reconstitution math (10 mg vial + 2 mL BAC water)
Step overview (educational reference)
1.Add 2.0 mL bacteriostatic water to a 10 mg vial.
2.Allow peptide to dissolve (typically ~15–20 minutes).
3.Gently swirl — do NOT shake.
Final concentration
•Total peptide = 10 mg
•Total liquid volume = 2 mL
Concentration:
•5 mg/mL
•= 5000 mcg per mL
In experimental or anecdotal research discussions, two general approaches are often referenced:
1) Loading phase model
•Duration often described: ~4–6 weeks
•Example range:
~2.0–2.5 mg subcutaneously twice weekly
Total weekly exposure:
approximately 4–5 mg/week
Purpose in research context:
•Achieve steady exposure during early study phase.
⸻
2) Maintenance phase model
After loading period:
~2.0–2.5 mg once weekly
(or sometimes every 10–14 days depending on experimental design).
⸻
3) Alternative micro-dosing model (research references)
Some sources describe:
•500–1000 mcg daily
•Gradual titration upward
Weekly exposure typically ends up similar:
~3.5–7 mg/week total.
For following example:
If solution = 5 mg/mL:
•2.5 mg dose:
2.5 ÷ 5 = 0.5 mL
0.5 mL = 50 units on U-100 syringe.
Common lab handling references include:
•Use sterile technique during reconstitution.
•Swirl gently rather than shaking.
•Refrigerate after reconstitution.
•Protect from light.
•Many sources mention ~4–6 weeks refrigerated stability (depends on preparation conditions).